Have little left to give. What to do when MIL chooses to give up and not help self...I think I just don't want to help anymore either?

Is she broke? She may qualify for medicade. Next major illness or fall- call 911. Refuse to pick her up. They'll have to place her. She'll spend all her money and they'll have to put her on medicade.

I did not anticipate the extent of these problems. Wife doesn't want to talk about it. After 35 years you would think I knew the two together, I didn't. They just don't like or respect each other. Short visits were a whole different thing.
MIL is beyond taking care of herself. Had a serious fall 7 months ago--didnt break anything but it took a toll. Refused to go to hospital and ended up here because that was the last straw. She can't self administer meds other than eye drops; can't prepare food and can't be trusted to eat if left to self. The only other choice I see is forcing her into a nursing home somehow and there is no money to do that. It is us or the street to die.

You've got your hands full and if your wife (her daughter) is leaving a lot of the work to you, that's not fair to you. Did you discuss how things would work before MIL moved in? Did you foresee any of these issues and how did you think they'd be resolved?

Sounds like you and your wife need to have a good sit-down discussion of how things are going. Maybe it's time for MIL to move somewhere else. Could she move to a senior living apartment or independent/assisted living nearby?