I'm caring for my frustrated sister and mom at the same time. Any advice?

My mom is under home care. My sister had surgery about a week and a half ago and is having to use a wheelchair and walker to get around. She has arthritis on top of this, and is having stiffness and pain, and cannot stand for very long periods of time. She is frustrated and down. This morning, our mom kept asking her why she was having so much trouble and had to ask me to do so much for her. Mom, who has always been very independent, and was raised this way, is also down about her own condition, frustrated, and they both cannot seem to wrap their minds around why they need so much help. This morning, they got on each other's nerves before I left for work. It has been less than 3 weeks and I am already exhausted. Some days, I want to run away and not come back.