How can I motivate my LO with Alzheimer’s not to sleep all day?

you can't motivate a person with dementia to do anything. but aside from that, sleeping during the day is very common among dementia sufferers so it's not just a motivational issue. my mom was sleeping all day and up all night terrorizing us until she got to memory care. the disruption and the enforced schedule of memory care managed to get her on a more normal sleeping schedule but no amount of verbal persuading would ever have done it.

I think it would be really hard to motivate someone to stay awake who has medication causing them to sleep. Check with her doctor. They may suggest it takes awhile to adjust or that the meds are too strong or it’s the wrong Med. some recommend a geriatric psychiatrist to manage these type meds.
I am sure there was a reason the Med was prescribed. Sometimes the choices aren’t great.

Your wife should not be left alone at home if she is experiencing anxiety and depression with Alzheimer's Disease and is being medicated for it, assuming you ARE leaving her home alone. It's dangerous to leave her alone, so my suggestion is to stop doing so and to hire a caregiver to stay with her while you are gone at work.

Please look into getting your wife a caregiver and/or getting her into daycare while you are gone at work. In the meantime, speak to her doctor about the increased dose of her anxiety/depression medication as well, which may be having a negative effect on her and causing her to sleep too much. Your wife is not very 'elderly' as the other comment suggests, so check in with her doctor about this new change that's come about. Any time there is a behavioral change when meds are increased, it's time to call the doctor. My mother suffered from dementia for years and was taking Wellbutrin (max dose, too) for a very long time without "severe sedation and weakness" as a side effect! AND she WAS elderly; 92-95 years old when she was taking the maximum dose of 'psychotropic' medication for her anxiety & depression.

 It's not usually possible to 'motivate' an Alzheimer's sufferer to do much of anything; are you familiar with AD and the mechanisms of the disease?

To better understand AD, I suggest you read this 33 page booklet (a free download) which has THE best information ever about managing AD/dementia and what to expect with a loved one who's been diagnosed with it.

Understanding the Dementia Experience, by Jennifer Ghent-Fuller 
https://www.smashwords.com/books/view/210580

Jennifer is a nurse who worked for many years as an educator and counsellor for people with dementia and their families, as well as others in caring roles. She addresses the emotional and grief issues in the contexts in which they arise for families living with dementia. The reviews for her books are phenomenal b/c they are written in plain English & very easy to read/understand. Her writings have been VERY helpful for me.

The full copy of her book is available here:
https://www.amazon.com/Thoughtful-Dementia-Care-Understanding-Experience/dp/B09WN439CC/ref=sr_1_2?crid=2E7WWE9X5UFXR&keywords=jennifer+ghent+fuller+books&qid=1657468364&sprefix=jennifer+ghent%2Caps%2C631&sr=8-2

She also has published a workbook entitled, “It Isn’t Common Sense: Interacting with People Who Have Memory Loss Due to Dementia.”

https://www.amazon.com/Isnt-Common-Sense-Interacting-Dementia/dp/1481995995/ref=sr_1_4?crid=2E7WWE9X5UFXR&keywords=jennifer+ghent+fuller+books&qid=1657468655&sprefix=jennifer+ghent%2Caps%2C631&sr=8-4


Good luck to both you and your wife as you travel this road together; it can be very challenging, I know.

Psychotropic medication causes severe sedation and weakness in the elderly.