One of my parents is in charge of dispensing medications for both and recently I have questioned a daily Benadryl tablet taken by one. The doctor has listed the medication "as Needed" but it is still being taken every day and also know that a glass of wine is had sometimes so I am not sure of this interaction- if the meds are even effective since taken every day for 30 yrs?
But if they are taking more than one pill and more than one glass of wine every night, there's a good possibility they have been doing this for a while and need more to overcome a tolerance.