Her pills are mainly for blood pressure and just recently, a pill for acid reflux was added. Never know how she will react. She could be laughing one minute and then sees the pills and hides them or throws them in extreme anger. Dementia has set in. So hard!
If you can be reasonably confident that she'll be on her best behaviour in, say, the mornings, you could ask her doctor or pharmacist if her px can be changed to a once a day formulation. For your own peace of mind, also take their advice on what to do if she chews and only partially spits out a tablet - forget about it, try again later, or what.
The acid reflux pills - what sort? If they're standard antacids like Rennies or Gaviscon or Tums, try switching to a liquid formula and see if she's happier with that. If they're PPIs, with a name that will usually end in -azole, you have a problem because they have to be taken intact - you can't dissolve them or break them up; or at least you *can* but oh my goodness it's a performance under time pressure and there's still a risk that your elder will just spit it out of the corner of her mouth.
You can only do your best. You can change the formulation, you can mix the tablets with things she finds enjoyable like yoghurt or ice cream or applesauce, you can provide a "chaser" like a chocolate or a piece of fudge and use straight bribery.
But in the end, if nothing's working, then she doesn't get that dose and that's that - and you might well find that her doctor isn't nearly as worried about it as you are.
I am so sorry that she has become combative, dementia is the toughest journey for caregivers. Be kind to yourself and hugs for all you do.